All compounded phenomena, including materiality and the mind, are in a state of constant flux and therefore not permanent. This is referred to as “impermanence (annica)” in Buddhism. This means that human beings are born and grow old, get sick and die. In addition, all phenomena are impermanent because all things arise, exist and cease in relation to other things. All beings in the cycle of dependent arising are impermanent and always in a state of continual change. 

"Bhikkhus! All phenomenal things are impermanent and have the nature of ceasing upon arising. Things are not solid and have no substance. There is neither ultimate dimension nor enjoyable aspects in phenomena. Thus, bhikkhus should persevere in their practice and seek liberation."
- Saptasuryoda Sutra

- excerpt from Buddhist English (Elementary 2) published in 2014 by the Jogye Order of Korean Buddhism​​​